- family: Theraphosidae
- genus: Holothele
- species: Holothele colonica (Simon, 1889)
- species: Holothele culebrae (Petrunkevitch, 1929)
- species: Holothele denticulata (Franganillo, 1930)
- species: Holothele incei (Cambridge, 1898)
- species: Holothele longipes (L. Koch, in Ausserer, 1875)
- species: Holothele ludwigi (Strand, 1907)
- species: Holothele recta Karsch, 1879
- species: Holothele rondoni (Lucas & Bücherl, 1972)
- species: Holothele sanguiniceps (Cambridge, 1898)
- species: Holothele sericea (Simon, 1903)
- species: Holothele shoemakeri (Petrunkevitch, 1926)
- species: Holothele steini (Simon, 1889)
- species: Holothele sulfurensis Maréchal, 2005
- species: Holothele vellardi Rudloff, 1997
- species: Holothele waikoshiemi Bertani & Araújo, 2006